Live
Webinar
Recording coming soon
From Cytokines to CYP Enzymes: Understanding Inflammation-Driven Changes in Detoxification Pathways
Speakers
Matt Reddy, ND
September 17, 2026
2 PM EDT
A recording of the webinar will be available to watch 24-48 hours after the live session ends.
Chronic inflammation is increasingly recognized not only as a contributor to disease but also as a modulator of the body’s detoxification systems. This webinar examines how key pro-inflammatory cytokines can alter Phase 1, 2, and 3 pathways—particularly through changes in CYP enzymes, conjugation processes, and transporters—and explores practical strategies, including natural compounds, which may help restore balance.
Key takeaways
- Review how pro-inflammatory cytokines (IL-6, TNF-α, IL-1β) may potentially suppress some CYP enzymes, Phase 2 conjugation pathways, and Phase 3 transporters, impairing overall detoxification.
- Learn the bidirectional cycle in which reduced Phase 1–3 capacity may lead to toxin accumulation that can further contribute to inflammation and oxidative stress.
- Apply clinical strategies to address this impairment, including identifying inflammation drivers and the supportive use of natural compounds such as omega-3 fatty acids and curcumin to help promote resolution of inflammation and potentially restore detoxification capacity.
