Epigenetics and Aging: Exploring TruAge and TruHealth Testing
Speakers
Adiv Johnson, PhD
This webinar will explore the science of epigenetics and aging, with a focus on TruDiagnostic’s TruAge and TruHealth testing.
Dr. Adiv Johnson will discuss DNA methylation-based epigenetic aging clocks, including research on associations between certain epigenetic biomarkers and all-cause mortality in longitudinal data. The presentation will also cover non-clock epigenetic biomarkers, including methylation-derived estimates that may be associated with C-reactive protein and telomere length. Illustrative case studies will be shared to explore the interpretation and limitations of epigenetic data in real-world settings.
Key takeaways
- Describe how DNA methylation patterns are used to construct epigenetic biomarkers of aging.
- Distinguish epigenetic aging clocks from other methylation-derived biomarkers and recognize the different types of information they are designed to provide.
- Discuss research examining relationships between epigenetic biomarkers, aging-related measures, and health outcomes, including important limitations of these associations.
- Identify the types of epigenetic data reported through TruAge and TruHealth testing and key considerations when reviewing results.
- Apply a critical framework to illustrative cases, including how to contextualize epigenetic findings alongside other available information and avoid overinterpreting individual results.

