Gastrointestinal health: Labs and supplements
December 13, 2024
Protocol development in integrative medicine is not typically a simple process. Individuals require individualized care, and what works for one patient may not work for another.
To establish these protocols, we first developed a Rating Scale that could be used to discern the rigor of evidence supporting a specific nutrient’s therapeutic effect.
The following protocols were developed using only A through C-quality evidence.The gut’s influence extends beyond digestion, impacting immune function, mental health, and overall well-being through its diverse microbiome. This ecosystem communicates with the brain. Maintaining gut health through diet, lifestyle, and stress management is crucial. Functional gastrointestinal (GI) testing offers comprehensive insights into the microbiome and digestive function enabling practitioners to develop personalized plans, supporting optimal health outcomes.
Labs
The GI360™ test by Doctor’s Data is a comprehensive stool analysis that provides detailed insights into GI health using multiple testing methodologies. It evaluates gut microbial conditions, digestion/absorption markers, and inflammation indicators, screening for over 80 microorganisms including bacteria, parasites, and fungi. The test offers a broad assessment of the gut microbiome, digestive function, and potential pathogens, enabling healthcare providers to develop personalized plans for various GI and systemic health issues.
The GI-MAP® by Diagnostic Solutions Laboratory is a comprehensive stool analysis that uses quantitative PCR technology to assess the GI microbiome and detect pathogens. It evaluates bacterial, viral, and parasitic pathogens, normal flora, opportunistic bacteria, fungi, and markers of digestion, inflammation, and immune function. The test provides detailed quantitative results that allow healthcare providers to determine the clinical significance of findings and develop personalized protocols to address gut dysfunction and underlying imbalances.
The GI Effects® Comprehensive Stool Profile by Genova Diagnostics is an advanced stool test that provides a comprehensive assessment of GI health. It evaluates digestive function, intestinal inflammation, and the gut microbiome using multiple methodologies to analyze biomarkers related to digestion/absorption, inflammation/immunology, and microbial balance. The test offers detailed insights into potential root causes of GI symptoms, allowing healthcare providers to develop personalized plans that address underlying imbalances.
Herbal microbiome-support supplements
Herbal supplements can increase beneficial bacteria. Many herbs contain prebiotic polyphenols that nourish gut bacteria and promote the growth of probiotics like Lactobacillus and Bifidobacteria. Some herbs also show effects on healthy levels of yeasts and other organisms.
1.5 ml of extract in a small amount of water, 3-4 times daily between meals.
1,000–2,000 mg, 2–3 times per day
500–1,000 mg, 1-2 times per day
200 mg, 2–3 times per day
300–500 mg, three times per day (berberine)
1 tsp, three times per day
100–500 mg, 2–3 times per day
General digestive-support supplements
Digestive enzymes and prebiotics are crucial for optimal digestive health and nutrient absorption. Enzymes, produced by the pancreas, mouth, and small intestine, break down food into absorbable nutrients. Insufficient enzyme levels can cause bloating, gas, and nutrient deficiencies. Prebiotics are non-digestible fibers that nourish beneficial gut bacteria, promoting a healthy gut microbiome essential for digestion and immune function. Together, enzymes and prebiotics work synergistically to support efficient nutrient extraction, maintain a healthy gut environment, and enhance overall well-being by facilitating proper digestion and fostering a balanced gut microbiome.
Dosing may vary depending on the specific product and should be tailored to the individual’s nutritional needs and goals, such as enzyme repletion or metabolic support. Healthcare providers should consult product-specific guidelines and adjust the dosage based on the patient’s unique requirements and response.
3–5 g per day
Inflammation-support supplements
Certain herbs can significantly enhance GI health by supporting healthy inflammation balance and soothing the digestive tract. Key herbs include turmeric, which contains curcumin; ginger, known for its properties and ability to promote digestive enzyme production; omega-3 fatty acids, which support gut microbiome diversity; and marshmallow root, which helps soothe the digestive tract and protect the gut lining. Incorporating these herbs into a gut health regimen can promote overall GI wellness.
500–1,000 mg per day (adjust dose based on testing)
500–2,000 mg per day (adjust dose based on testing)
1–3 tsp in 240 mL of water, up to three times per day (adjust dose based on testing and form)
250 mg to 2 g per day given in 3–4 divided doses (adjust dose based on testing and form)
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