Many over-the-counter and prescription medications have been shown to negatively influence nutrient digestion, absorption, distribution, metabolism, function, catabolism, and excretion, which can lead to depletions and possible related illnesses over time.

This chart primarily includes drug-nutrient depletions for which evidence from systematic reviews, meta-analyses, and randomized, double-blind, placebo-controlled, or randomized controlled human trials were available. The pharmaceuticals included in this table are among the top-selling medications in the United States.

Authors

Alex Keller, ND

Medical Director

Dr. Alex Keller is a licensed and practicing naturopathic doctor in Ottawa, Canada and the medical director at Fullscript. As medical director, he oversees the Integrative Medical Advisory team (IMAT) and the development of educational content for practitioners across North America. He is a graduate of the University of Ottawa with an HBSc in Health Sciences and Psychology. Although originally planning to attend conventional medical school, Dr. Keller shifted direction and completed a degree in naturopathic medicine at the Canadian College of Naturopathic Medicine. The shift followed a three-month internship at a rural Kenyan hospital where he worked with doctors who used local food to successfully treat patients, after which he felt compelled to practice a diet-oriented system of medicine. Today, he splits his time working for Fullscript, seeing patients, and developing an innovative regenerative farming operation. He lives with his wife Jenn and their two children on a 50-acre farm outside Ottawa.

Ross Bailey, MKin, BScKin

Lead Analyst, Medical Innovation

Ross graduated from Queen’s University with a Bachelor of Science specializing in kinesiology, then completed a Master’s in Kinesiology at Western University. At Western, he worked as a teaching assistant in the cadaver labs for undergraduate anatomy courses. Ross enjoys conducting in-depth research reviews on a variety of medical topics and is an advocate for evidence-based decision support. He actively engages in continuing education on subjects like research methods in systematic reviews and meta-analyses, supplement quality standards, and the regulation of sports nutrition.